@
yidinghe 问了,以下是答案(非原文,我自己总结的),现代药理学已经通过分子生物学、细胞培养、动物实验及组学分析(如转录组学、代谢组学)建立了相对完备的证据链,具体来说是:激活 VEGF/VEGFR2 血管新生通路、激活 TGF-β/Smad 信号通路、调控 NF-κB 炎症通路、促进 I/III 型胶原蛋白基因表达等等机制,来加速黏膜修复和抗炎。参考文献是很多的,有兴趣可以自己看:1.Periplaneta americana extract (Kangfuxin) accelerates wound healing through activating the TGF-β/Smad signaling pathway and promoting collagen synthesis 2. Kangfuxin liquid attenuates dextran sulfate sodium-induced ulcerative colitis in mice via suppressing the NF-κB/NLRP3 inflammasome pathway 3. Periplaneta americana extract promotes angiogenesis and protects against ethanol-induced gastric mucosal injury via VEGF/VEGFR2 pathway and antioxidant system 4. Bioactive components from Periplaneta americana stimulate skin fibroblast proliferation and cell cycle progression via Cyclin D1 upregulation